Journal: Photonix

Article Title: Computational optical streak microscopy of megahertz acoustic microbubble dynamics

doi: 10.1186/s43074-026-00232-8

Figure Lengend Snippet: COSDUM of stable cavitation in insonated microbubbles. a Time-resolved microbubble radial oscillations with representative frames showing microbubble dynamics in one ultrasound cycle (marked by the cyan dashed cuboid). b Quantification of the time-resolved radius (red solid line) and the wall velocity \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${v}_{\mathrm{w}}$$\end{document} v w (blue dotted line) of the microbubble. c Power spectrum of the time-resolved radius extracted from (b). d Angular distribution of microbubble radius at rest and at peak expansion over 10 cycles. e–h Quantification of the expansion ratio \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${r}_{\mathrm{e}}$$\end{document} r e (e), the compression ratio \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${r}_{\mathrm{c}}$$\end{document} r c (f), the oscillation asymmetry \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${r}_{\mathrm{a}}$$\end{document} r a (g), and maximum wall velocity \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${v}_{\mathrm{mw}}$$\end{document} v mw (h) across 17 measured microbubbles. The red dotted curves in (e)–(g) were obtained by fitting the experimental data with a fourth-order polynomial. The red dotted curve in (h) was obtained by linear regression fitting

Article Snippet: Encapsulated perfluoropropane microbubbles (Lantheus Medical Imaging, DefinityTM) were first diluted by adding one drop of the commercial microbubble suspension into a 1.5-mL microcentrifuge tube containing distilled water and were then gently mixed to ensure uniform dispersion.

Techniques:

Journal: Photonix

Article Title: Computational optical streak microscopy of megahertz acoustic microbubble dynamics

doi: 10.1186/s43074-026-00232-8

Figure Lengend Snippet: COSDUM of the collapse of an insonated microbubble. a Time-resolved microbubble radial oscillations with representative frames showing microbubble dynamics in one ultrasound cycle (marked as the cyan dashed cuboid). b Quantification of the radial profile of the microbubble over time (red solid line) with its radial wall velocity profile \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${v}_{\mathrm{w}}$$\end{document} v w (blue dotted line). c Radial power spectrum extracted from ( b )

Article Snippet: Encapsulated perfluoropropane microbubbles (Lantheus Medical Imaging, DefinityTM) were first diluted by adding one drop of the commercial microbubble suspension into a 1.5-mL microcentrifuge tube containing distilled water and were then gently mixed to ensure uniform dispersion.

Techniques:

Journal: Photonix

Article Title: Computational optical streak microscopy of megahertz acoustic microbubble dynamics

doi: 10.1186/s43074-026-00232-8

Figure Lengend Snippet: COSDUM of microbubble-platelet interactions in whole blood. a Representative reconstructed frames showing the periodic motion of a platelet driven by an uncontacted microbubble. b Close-up view of the platelet during three representative oscillation cycles. c Quantification of the radial profile of the microbubble over time. d–e Central position of the platelet along the \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$x$$\end{document} x - and \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$y$$\end{document} y -axes, respectively

Article Snippet: Encapsulated perfluoropropane microbubbles (Lantheus Medical Imaging, DefinityTM) were first diluted by adding one drop of the commercial microbubble suspension into a 1.5-mL microcentrifuge tube containing distilled water and were then gently mixed to ensure uniform dispersion.

Techniques:

Journal: Photonix

Article Title: Computational optical streak microscopy of megahertz acoustic microbubble dynamics

doi: 10.1186/s43074-026-00232-8

Figure Lengend Snippet: COSDUM of microbubble-red blood cell (RBC) interactions in whole blood. a Representative reconstructed frames showing the shape-adapted expansion of a microbubble around an adjacent RBC, resulting in a contact surface of approximately 25% of the RBC. b Microbubble radius as a function of angle and time. c 2D projected area of the microbubble over time, highlighting periodic oscillations and inter-cycle variations

Article Snippet: Encapsulated perfluoropropane microbubbles (Lantheus Medical Imaging, DefinityTM) were first diluted by adding one drop of the commercial microbubble suspension into a 1.5-mL microcentrifuge tube containing distilled water and were then gently mixed to ensure uniform dispersion.

Techniques: